Język: Angielski

The significance of CD44 and HMMR receptor expression on sperm surface in interaction with hyaluronic acid during fertilization

Fertilization is a complex process involving molecular interactions focused on recognition, binding, and fusion with the egg. Roughly 30% of couples seeking infertility treatment experience idiopathic infertility despite being otherwise healthy. The causes of this condition can be attributed to the biochemical and genetic properties of sperm.

Hyaluronic acid (HA) receptors on the sperm surface play a crucial role in fertilization, particularly in adhesion to the cumulus oophorus and initiating cell rotation signals. CD44 on sperm serves as a biomarker of maturity and quality, reflecting their ability to interact with the egg. The expression level of CD44 and HMMR receptors may be associated with female partner preference, known as „cryptic female choice,” and can influence fertilization success. Variability in the number and types of receptors on sperm surface can affect their ability to bind effectively with the egg, directly impacting the efficiency of assisted reproduction procedures like IVF (in vitro fertilization).

During the presentation, we will discuss the impact of HA, HMMR, and CD44 receptor gene expression on sperm quality. The goal of future research is to better understand the role of these receptors in fertilization and improve diagnostic methods in infertility treatment. Monitoring these receptors can help identify causes of infertility and facilitate the selection of appropriate medical procedures.

Keywords: Fertilization, hyaluronic acid receptors, sperm, CD44, diagnostics.

Biological Basis of Well-Being by SciClub

Biological Basis of Well-Being by SciClub features young researchers presenting research on how biological, psychological, and environmental factors shape health and behavior. Topics include gut microbiome links to social decision-making, personality, inflammation, and depression; synbiotic interventions for better cognitive performance and relaxation; academic stress reduction; and hyperbaric oxygen therapy. The panel offers fresh, interdisciplinary insights into mental and physical well-being.

Protein Biochemistry

Panel dedicated to biochemical characterization of proteins – the basic building blocks of any living organism. Research presented as part of the panel may include topics like: mutagenesis, enzymatic activity, protein-ligand interactions, complex formation, structural characterization, medical applications, phylogenetic studies, theoretical calculations and many others.

Molecular Biology: Advancing the Future of Medicine

Panel will explore how molecular techniques are shaping modern medicine. Topics will include the application of genetic research in diagnostics, personalized medicine, and the development of targeted therapies, highlighting its potential to revolutionize disease treatment and prevention.

Medicinal chemistry

Keywords: medicinal chemistry, drug design, synthesis of bioactive compounds, drug-receptor interactions, peptide and protein chemistry, pharmaceutical chemistry, protein and peptide engineering, anticancer drugs, targeted therapies, enzyme inhibitors, bioconjugation, new drug carriers

Reassessing Power: Foucault’s Legacy in Historical and Contemporary Research

Over the past two decades, Michel Foucault’s work has continued to inspire and challenge scholars across a wide spectrum of disciplines. His analyses of *raison d’État*, governmentality, and biopolitics remain particularly relevant for scholars of modern history, political theory, and cultural studies. Far from being confined to one academic field, Foucault’s conceptual tools offer a flexible and dynamic framework for interrogating the evolution of state power, the organization of knowledge, and the mechanisms of social control.

Michel Foucault has proved to be an invaluable hermeneutical toolkit for recent socio-political developments. The Covid pandemic and biopolitics, the persistence of neoliberalism and its effects on life. The most recent research done on Foucault as an instigator of economic theology (Stimilli 2015) or recent works on the linkage between Foucault and the Reformation (Lindholm and Di Carlo 2024), Foucault and Tacitus (Di Carlo 2024, Ferraro 2024) and Foucault and the US Supreme Court (Di Carlo 2024b) prove the importance and the significance of Foucault.

This panel invites contributions that engage with Foucault’s theoretical legacy, whether by applying his concepts to new historical contexts, reflecting on his methodological approach, or reassessing his ideas in light of contemporary geopolitical transformations. We are especially interested in papers that explore how Foucault’s reflections on state power and the art of government can inform current debates on global governance, authoritarianism, and political resistance.

In addition, the panel seeks to highlight the impact of Foucault’s thought on subjects as diverse as linguistics, law, and film studies. We welcome interdisciplinary proposals that either extend Foucault’s methodologies to new domains or critically engage with his intellectual legacy to shape future academic research.

Scholars working in history, philosophy, political science, sociology, linguistics, and related fields are encouraged to submit proposals. The panel aims to foster a rich dialogue on the contemporary significance of Foucault’s work and its ongoing potential for scholarly advancement.

Art as a Means of Communication in Second Language Learning

This panel explores the role of art as a communicative tool in second language acquisition and learning. Drawing from interdisciplinary research, the panellists will discuss how visual expression enhances linguistic development, fosters cultural understanding, and aids learners in overcoming language barriers, broadening their understanding, and expanding their horizon. Topics include the integration of art in language classrooms, the impact of creative expression on cognitive processes, and practical applications for educators. The session will conclude with an interactive discussion on best practices for using art in second language instruction.